High Street was renamed as Vernor sometime in the early 20th century. Vernor Highway was an amalgamation of various pre-exisiting streets to make a single cross-town highway.
In so far as I know, those streets were, from east to west, Waterloo, German, High, Dix, and Ferndale. The piece of W. Vernor that goes past Michigan Central and through the infamous tunnel under the tracks was built to link the High St. and Dix Rd. portions.
The formerly High St. portion of Vernor was destroyed to build the Fisher Fwy. [[I-75) in the late '60s. For many years there was still a couple of rows of old Vernor/High St. victorian houses left standing on the south service drive of the freeway, including famous Detroit jazz venue the Rapa House.
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