The area around Wayne State University, midtown, is relatively safe. The worst thing that might happen to you, as in any other major city, is you might be panhandled, or become the victim of property crime. If you mind your own business and don't go seeking trouble [[drugs) then you should not have a problem. People ignorantly assume that abandonment means their chances of becoming a victim of crime increase dramatically, but that is simply not true. I have been to the city hundreds of times and have never had a problem. I have witnessed crazy behavior, but that is hardly unique to Detroit.