Herman Keifer makes the most sense. They could partner with the current owners and redevelop the main hospital building into housing or offices as well. It's also close to Henry Ford Health and could plausibly included in their expansion plans. Don't put more sports facilities downtown when downtown needs mixed-use density instead.

The other downside of a I-375 site is you're talking about a hypothetical probably 5-10 years away from happening, at the rate MDOT is moving.

If MLS ever does come back, put them at the SW Hospital site in Corktown.