St. Elsewhere. The show took on controversial topics long before it was the norm.
WKRP in Cincinnati
M*A*S*H
Newheart [[the one where he owns and Inn) and where he was a psychologist
Murphy Brown for Grant Shaud's performances
South Park for its irreverence towards everything
Futurama
Northern Exposure for its portrayals of native Americans
Fawlty Towers for the manic performances of Cleese and the actor playing the Spanish waiter
Black Adder
Rocky and Bullwinkle